Error message
Warning: rename(sites/default/files/php/twig/.IdelSLni7Ky91Bx_Inq7YK9tI0E,sites/default/files/php/twig/678527e9ce390_video-embed-iframe.html.t_Fk4o4wVtnFrnWpKy02NU5EK5l/BtVMKAiFJr1310no53-n28CwRm1G-JdT-rtweeyMYzA.php): No such file or directory in Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (line 88 of core/lib/Drupal/Component/PhpStorage/MTimeProtectedFastFileStorage.php).Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save('678527e9ce390_video-embed-iframe.html.t_Fk4o4wVtnFrnWpKy02NU5EK5l', '<?php use Twig\Environment; use Twig\Error\LoaderError; use Twig\Error\RuntimeError; use Twig\Extension\SandboxExtension; use Twig\Markup; use Twig\Sandbox\SecurityError; use Twig\Sandbox\SecurityNotAllowedTagError; use Twig\Sandbox\SecurityNotAllowedFilterError; use Twig\Sandbox\SecurityNotAllowedFunctionError; use Twig\Source; use Twig\Template; /* modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig */ class __TwigTemplate_68a5713466cc31ee3685cf364418d1f4 extends \Twig\Template { private $source; private $macros = []; public function __construct(Environment $env) { parent::__construct($env); $this->source = $this->getSourceContext(); $this->parent = false; $this->blocks = [ ]; $this->sandbox = $this->env->getExtension('\Twig\Extension\SandboxExtension'); $this->checkSecurity(); } protected function doDisplay(array $context, array $blocks = []) { $macros = $this->macros; // line 7 echo "extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["attributes"] ?? null), 7, $this->source), "html", null, true); if ( !twig_test_empty(($context["url"] ?? null))) { echo " src=\""; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["url"] ?? null), 7, $this->source), "html", null, true); if ( !twig_test_empty(($context["query"] ?? null))) { echo "?"; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, twig_urlencode_filter($this->sandbox->ensureToStringAllowed(($context["query"] ?? null), 7, $this->source)), "html", null, true); } if ( !twig_test_empty(($context["fragment"] ?? null))) { echo "#"; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["fragment"] ?? null), 7, $this->source), "html", null, true); } echo "\""; } echo "> "; } public function getTemplateName() { return "modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig"; } public function isTraitable() { return false; } public function getDebugInfo() { return array ( 39 => 7,); } public function getSourceContext() { return new Source("", "modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig", "/srv/www/web/modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig"); } public function checkSecurity() { static $tags = array("if" => 7); static $filters = array("escape" => 7, "url_encode" => 7); static $functions = array(); try { $this->sandbox->checkSecurity( ['if'], ['escape', 'url_encode'], [] ); } catch (SecurityError $e) { $e->setSourceContext($this->source); if ($e instanceof SecurityNotAllowedTagError && isset($tags[$e->getTagName()])) { $e->setTemplateLine($tags[$e->getTagName()]); } elseif ($e instanceof SecurityNotAllowedFilterError && isset($filters[$e->getFilterName()])) { $e->setTemplateLine($filters[$e->getFilterName()]); } elseif ($e instanceof SecurityNotAllowedFunctionError && isset($functions[$e->getFunctionName()])) { $e->setTemplateLine($functions[$e->getFunctionName()]); } throw $e; } } } ') (Line: 112) Drupal\Core\Template\TwigPhpStorageCache->write('678527e9ce390_video-embed-iframe.html.t_Fk4o4wVtnFrnWpKy02NU5EK5l', '<?php use Twig\Environment; use Twig\Error\LoaderError; use Twig\Error\RuntimeError; use Twig\Extension\SandboxExtension; use Twig\Markup; use Twig\Sandbox\SecurityError; use Twig\Sandbox\SecurityNotAllowedTagError; use Twig\Sandbox\SecurityNotAllowedFilterError; use Twig\Sandbox\SecurityNotAllowedFunctionError; use Twig\Source; use Twig\Template; /* modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig */ class __TwigTemplate_68a5713466cc31ee3685cf364418d1f4 extends \Twig\Template { private $source; private $macros = []; public function __construct(Environment $env) { parent::__construct($env); $this->source = $this->getSourceContext(); $this->parent = false; $this->blocks = [ ]; $this->sandbox = $this->env->getExtension('\Twig\Extension\SandboxExtension'); $this->checkSecurity(); } protected function doDisplay(array $context, array $blocks = []) { $macros = $this->macros; // line 7 echo "extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["attributes"] ?? null), 7, $this->source), "html", null, true); if ( !twig_test_empty(($context["url"] ?? null))) { echo " src=\""; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["url"] ?? null), 7, $this->source), "html", null, true); if ( !twig_test_empty(($context["query"] ?? null))) { echo "?"; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, twig_urlencode_filter($this->sandbox->ensureToStringAllowed(($context["query"] ?? null), 7, $this->source)), "html", null, true); } if ( !twig_test_empty(($context["fragment"] ?? null))) { echo "#"; echo $this->extensions['Drupal\Core\Template\TwigExtension']->escapeFilter($this->env, $this->sandbox->ensureToStringAllowed(($context["fragment"] ?? null), 7, $this->source), "html", null, true); } echo "\""; } echo "> "; } public function getTemplateName() { return "modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig"; } public function isTraitable() { return false; } public function getDebugInfo() { return array ( 39 => 7,); } public function getSourceContext() { return new Source("", "modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig", "/srv/www/web/modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig"); } public function checkSecurity() { static $tags = array("if" => 7); static $filters = array("escape" => 7, "url_encode" => 7); static $functions = array(); try { $this->sandbox->checkSecurity( ['if'], ['escape', 'url_encode'], [] ); } catch (SecurityError $e) { $e->setSourceContext($this->source); if ($e instanceof SecurityNotAllowedTagError && isset($tags[$e->getTagName()])) { $e->setTemplateLine($tags[$e->getTagName()]); } elseif ($e instanceof SecurityNotAllowedFilterError && isset($filters[$e->getFilterName()])) { $e->setTemplateLine($filters[$e->getFilterName()]); } elseif ($e instanceof SecurityNotAllowedFunctionError && isset($functions[$e->getFunctionName()])) { $e->setTemplateLine($functions[$e->getFunctionName()]); } throw $e; } } } ') (Line: 409) Twig\Environment->loadClass('__TwigTemplate_68a5713466cc31ee3685cf364418d1f4', 'modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig', NULL) (Line: 381) Twig\Environment->loadTemplate('modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig') (Line: 55) twig_render_template('modules/contrib/video_embed_field/templates/video-embed-iframe.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('video_embed_iframe', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array) (Line: 446) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 59) __TwigTemplate_63378ba314a6e7df1f5993c0d4058e3b->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('themes/custom/kodaweb/templates/system/field.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('field', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array) (Line: 446) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 51) __TwigTemplate_f7288a0ed9f00f45741d629563f8310e->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('modules/contrib/ds/templates/ds-1col.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('ds_1col', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 39) __TwigTemplate_2a24416c72b556c6672e8e2e26c2cb9b->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('modules/contrib/ds/templates/ds-entity-view.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('ds_entity_view', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 251) __TwigTemplate_dca7b4ff9ccc9e8fae56d0d0c5a50613->macro_content(Array, Array, Object) (Line: 1169) twig_call_macro(Object, 'macro_content', Array, 58, Array, Object) (Line: 187) __TwigTemplate_dca7b4ff9ccc9e8fae56d0d0c5a50613->macro_field(Array, Array, 'Videos', Object, Object, Object, Object, 1, Array) (Line: 1169) twig_call_macro(Object, 'macro_field', Array, 28, Array, Object) (Line: 83) __TwigTemplate_dca7b4ff9ccc9e8fae56d0d0c5a50613->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('modules/contrib/ds/templates/ds-field-expert.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('field', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array) (Line: 446) Drupal\Core\Render\Renderer->doRender(Array) (Line: 446) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 51) __TwigTemplate_f7288a0ed9f00f45741d629563f8310e->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('modules/contrib/ds/templates/ds-1col.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('ds_1col', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array) (Line: 479) Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 39) __TwigTemplate_2a24416c72b556c6672e8e2e26c2cb9b->doDisplay(Array, Array) (Line: 405) Twig\Template->displayWithErrorHandling(Array, Array) (Line: 378) Twig\Template->display(Array) (Line: 390) Twig\Template->render(Array) (Line: 55) twig_render_template('modules/contrib/ds/templates/ds-entity-view.html.twig', Array) (Line: 384) Drupal\Core\Theme\ThemeManager->render('ds_entity_view', Array) (Line: 433) Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 204) Drupal\Core\Render\Renderer->render(Array, ) (Line: 242) Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 580) Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 243) Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 132) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) call_user_func(Array, Object, 'kernel.view', Object) (Line: 142) Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch(Object, 'kernel.view') (Line: 174) Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 81) Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 58) Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 191) Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 128) Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 82) Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23) Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 718) Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
Dermatologist Dr Marius Rademaker discussed issues related to prescribing low-dose isotretinoin for acne in primary care. This included knowing when and how to initiate isotretinoin, monitoring and side effects, dosing and treatment duration.
Practitioner Resources
- Prescribing isotretinoin for patients with acne in primary care bpacnz (added 2017)
- Dermnet NZ isotretinoin topic
- SaferRx - isotretinoin
Patient Resources
- Acne, Health Navigator
- Isotretinoin, Health Navigator
- SafeRx - isotretinoin patient handout (2015)
- British Journal of Dermatology patient information handout (2015)
Presenter
Dr Marius Rademaker
BM (Soton) FRCP(Edin) FRACP DM FNZDS
Dr Rademaker is on the Board of the New Zealand Dermatological Society's successful web site, DermNet NZ, the Australasian Society for Dermatological Research, and the Australasian Journal of Dermatology. He has published over 150 articles and book chapters in the medical literature, and regularly lectures at international dermatology conferences.
In 2012 he published a paper that led to lower dose regimens for isotretinoin: Isotretinoin: dose, duration and relapse. What does 30 years of usage tell us?