Obesity management approaches

In this episode Ole Schmiedel discusses Mounjaro, a new weight loss drug, with a focus on its mechanism of action, practical use, side effects, nutritional considerations, and long-term safety. The conversation provides insights into how Mounjaro differs from previous GLP-1 receptor agonists, expected weight loss outcomes, and the importance of monitoring patients while on the medication.

Topics

Intro.
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How Mounjaro differs from previous generations of GLP one agonists.
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Common use cases.
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How much weight loss patients can expect.
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The practicalities of using Mounjaro
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Any contraindications?
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The first consultation.
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Monitoring for common side effects.
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Managing side effects.
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General monitoring regime.
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Self-monitoring regime.
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Preventing muscle mass loss.
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Long-term safety data.
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Take-home messages.
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Take home messages

Obesity is a chronic condition with no quick fix; however, alongside lifestyle work, we now have a great repertoire of modern medications to help with "significant weight loss".
It is important to have a long-term weight loss strategy, stressing exercise, dietary, and emotional components.
We are looking for improvements in obesity-related complications, not simply weight loss.
Strength-building exercise is really important to limit muscle loss.
These powerful medications can be used for a large number of patients, as long as they're affordable, with a clear outcome and a long-term approach.

Presenter

Ole Schmiedel

Consultant in Endocrinology, Diabetes, and General Internal Medicine

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Ole is a consultant in Endocrinology, Diabetes, and General Internal Medicine at Auckland District Health Board. He is the Service Clinical Director of Auckland Diabetes Centre. He qualified in medicine from Humboldt University, Berlin, Germany in 1997 and trained in endocrinology and diabetes at Cardiff University, Wales, UK. In 2009 he completed his specialist training in the UK and was awarded the Medical Doctorate for his work in the area of diabetes and microvascular complications.

Ole has been working as a physician and endocrinologist in New Zealand since 2009, and has expertise in all areas of diabetes management, with particular interests in type 2 diabetes, obesity, and medical weight management. In addition, he specialises in all areas of endocrinology including thyroid, adrenal, PCOS, bone health, male and female hormones.