In a recent Tools for Practice: Based on low-quality observational data, running likely does not increase the risk of developing osteoarthritis, except possibly in elite athletes.1
Additionally, recreational running may be associated with lowering the risk of knee osteoarthritis.
Exercise is one of the most effective treatments for reducing osteoarthritic pain for established osteoarthritis. There is a good podcast on this topic by the same authors where they say this is the best evidence to date.2