Primary care weight loss study confirms 36% with diabetes remission after 2 years

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Primary care weight loss study confirms 36% with diabetes remission after 2 years

Two-year follow up of the Diabetes Remission Clinical Trial (DiRECT) showed 36% of patients with sustained remission of type 2 diabetes (down from 46% at one year).1,2

Patients were diagnosed with type 2 diabetes within 6 years; aged 20-65 and BMI 27 to 45.

The intervention was delivered by a nurse or dietician in general practice after 8 hours of structured training. This consisted of total dietary replacement using a low energy formula diet (825-853 Kcal/day) for 3-5 months, followed by structured food reintroduction for 2-8 weeks and weight maintenance through sustained engagement.3

The intervention group had their BP and diabetes medication stopped initially and at 2 years only 40% of the intervention group required medication versus 83% in the control group.

This Gem was checked by Dr Carl Peters, Diabetologist at Waitemata DHB; one of the study investigators.

References:

  1. Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial. The Lancet (2019)  Click here 
  2. Type 2 diabetes is not for life. Newcastle University (2017) Click here
  3. Diabetes reversal advice from Newcastle University (2018) Click here

Gems are chosen by the Goodfellow director Dr. Bruce Arroll to be either practice changing or practice maintaining. The information is educational and not clinical advice.

 
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As published in NZ Doctor 22/05/2019