Primary care weight loss study results in 46% getting remission from diabetes

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Primary care weight loss study results in 46% getting remission from diabetes

In a RCT of a weight management programme, 46% of 306 participants remitted from their diabetes at one year (i.e. HBA1c <48 mmol/mol after being off medication for at least 2 months).1

The intervention was done by a nurse/ dietitian in general practice after 8 hours of structured training. Weight loss was by a total diet replacement phase using a low energy formula diet (825-853 Kcal/day) 59% carbohydrate, 13% fat, 26% protein, 2% fibre for 3 months extended up to 5 months, followed by structured food reintroduction for 2-8 weeks. Patients needed to be diagnosed with diabetes in the past 6 years; be aged 20-65 and BMI 27 to 45.

The intervention group had their BP and diabetes medication stopped. The weight loss was 10 kg (intervention) vs 1.0 kg (control). A quarter of those invited came into the study.

Reference:

  1. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet 2018.  Click here 

Gems are chosen by the Goodfellow director Dr. Bruce Arroll to be either practice changing or practice maintaining. The information is educational and not clinical advice.



As published in NZ Doctor 15/08/2018